Isolation, Phenotypic, Molecular and First-Time Proteomic Characterization of Human Mesenchymal Stem Cells (MSCs) Derived from Amniotic Fluid: Comparison to Bone Marrow MSCs.

Autor: Roubelakis, Maria G., Pappa, Kalliopi I., Bitsika, Vassiliki, Zagoura, Dimitra, Vlahou, Antonia, Papadaki, Helen, Antsaklis, Aristidis, Anagnou, Nicholas P.
Zdroj: Blood; November 2006, Vol. 108 Issue: 11 p4260-4260, 1p
Abstrakt: Human mesenchymal stem cells (hMSCs) constitute a population of multipotent cells, easily expanded in culture and able to give rise to many lineages. These characteristics make MSCs a very attractive tool for developing new strategies for clinical applications based on cell therapy. So far, the most common source of MSCs has been the bone marrow (BM). However, identification and characterization of alternative sources of MSCs is of great importance. One such alternative source is the amniotic fluid (AF), which can be collected during scheduled amniocentesis without any ethical concerns.
Databáze: Supplemental Index