| Autor: |
Hillier, M. C., Desrosiers, J.-N., Marcoux, J.-F., Grabowski, E. J. J. |
| Zdroj: |
Organic Letters; February 2004, Vol. 6 Issue: 4 p573-576, 4p |
| Abstrakt: |
The stereoselective displacement of a variety of chiral benzylic alcohols with triethylmethanetricarboxylate (TEMT) under Mitsunobu conditions (DEAD, PMe3) has been demonstrated to proceed in good yield (70−94%) and with a high degree of inversion. Subsequent saponification and decarboxylation of the products thus obtained provide chiral 3-aryl-3-substituted propanoic acids without racemization. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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