Prospective Multicenter Study for Evaluating Cognitive Disorders in Hematology-Oncology: A Pilot Study of 118 Patients

Autor: Rossi, Jean François, Laurier, Laurence, Misset, Jean-Louis, Spaeth, Dominique, Uwer, F., Soubeyran, Pierre, Largiller, Remy, Metges, Jean-Philippe, Blay, Jean- Yves, Attal, Michel, Facon, Thierry, Hermine, Olivier, Bugat, Roland, Spano, Jean-Philippe, Cals, Laurent, Cure, Hervé, Atlan, Dan, Gjoklaj, Mario
Zdroj: Blood; November 2008, Vol. 112 Issue: 11 p1309-1309, 1p
Abstrakt: Introduction:Cognitive impairment occurs in a subset of cancer survivors and is generally subtle. Most evidence suggests that chemotherapy may be a cause, although other factors associated with the diagnosis and treatment of cancer may contribute. Recently, recommendations for future research in evaluating cognitive disorders have been suggested though different published studies. Nevertheless, there is a need to standardize this evaluation, particularly for neuropsychological tests. The various domains to be explored include memory disorders, decrease in oral fluency, care and concentration, slowing down of information processing. The main objective of this prospective study was to assess the feasibility for evaluating cognitive disorders with neuropsychological tests in different groups of homogeneous patients. The secondary objectives were to evaluate the cognitive disorders in these groups of patients and the impact of disease and therapeutic strategies with a follow-up period of 48 weeks.
Databáze: Supplemental Index