| Autor: |
Vincelli, Iolanda D., Cufari, Patrizia, Di Raimondo, Francesco, Massimo, Martino, Gentile, Massimo, Morabito, Fortunato, Ciolli, Stefania, Rossi, Marco, Ronco, Francesca |
| Zdroj: |
Blood; December 2016, Vol. 128 Issue: 22 p5700-5700, 1p |
| Abstrakt: |
Hepatitis C virus (HCV) is a global health infection that affects about 170 million persons worldwide an it is the principal cause of chronic live-diseases. Progression to chronic disease occurs in the majority of HCV-infected persons, and infection with the virus has become the main indication for liver transplantation. Initial diagnosis of HCV infection is classically done by serologic methods either by determining anti HCV antibody and by determining the presence of HCV RNA . HCV encodes a virus-specific helicase, protease, and polymerase, and because of the critical function of these proteins in the viral life cycle, they represent attractive targets for antiviral therapy. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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