| Autor: |
Petruzziello, Fara, Giagnuolo, Giovanna, Cazzaniga, Giovanni, Beneduce, Giuliana, Locatelli, Franco, Stellato, Pio, Fazio, Grazia, Mirabelli, Giuseppe, Menna, Giuseppe, Parasole, Rosanna |
| Zdroj: |
Blood; November 2018, Vol. 132 Issue: 1, Number 1 Supplement 1 p5213-5213, 1p |
| Abstrakt: |
Recently, a novel subgroup of B Cell Precursor (BCP) Acute Lymphoblastic Leukemia (ALL), called Philadelphia-like(Ph-like) ALL, has been described. This high-risk group, despite the absence of BCR-ABL1rearrangement, shows genomic abnormalities that result in aberrant expression of cytokine receptors genes or tyrosine-kinase-activating signaling. These patients are poor responder to conventional chemotherapy but potentially sensitive to Tyrosine-Kinase Inhibitors (TKIs). |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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