| Autor: |
Ouyang, Hao, Sherman, Pamela J., Paschalis, Eleftherios P., Boskey, Adele L., Mendelsohn, Richard |
| Zdroj: |
Applied Spectroscopy; January 2004, Vol. 58 Issue: 1 p1-9, 9p |
| Abstrakt: |
Infrared spectroscopic imaging with 6–10 μm spatial resolution was used to characterize the changes in fracture callus mineral content, carbonate content, mineral crystallinity, and collagen maturity in femurs of 3-month-old ovariectomized rats treated with estrogen (estrogen sufficiency) or vehicle (estrogen deficiency). Comparisons were also made in these animals to cortical bone at a distance from the callus. Analyses at 4, 8, and 12 weeks post fracture demonstrated that healing was accelerated in the estrogen-sufficient animals as demonstrated by increasing mineral content and collagen maturity and decreasing carbonate incorporation. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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