Existence of Branched Side Chains in the Cell Wall Mannan of Pathogenic Yeast, Candida albicans

Autor: Shibata, Nobuyuki, Ikuta, Kyoko, Imai, Tomonori, Satoh, Yohko, Satoh, Richi, Suzuki, Atsuko, Kojima, Chizuko, Kobayashi, Hidemitsu, Hisamichi, Kanehiko, Suzuki, Shigeo
Zdroj: Journal of Biological Chemistry; January 1995, Vol. 270 Issue: 3 p1113-1122, 10p
Abstrakt: Isolation of side chain oligosaccharides from mannans of Candida albicansNIH B-792 (serotype B) and Candida parapsilosisIFO 1396 strains has been conducted by acetolysis under mild conditions. Structural study of these oligosaccharides by 1H and 13C NMR and methylation analyses indicated the presence of novel branched side chains with the following structures in C. albicansmannan. Manα1→3Manα1→2Manα1→2Manα1→2Man                               ↑  6                        Manα1                                                   Structure 1
Databáze: Supplemental Index