| Autor: |
Mickel, S. J., Sedelmeier, G. H., Niederer, D., Schuerch, F., Grimler, D., Koch, G., Daeffler, R., Osmani, A., Hirni, A., Schaer, K., Gamboni, R., Bach, A., Chaudhary, A., Chen, S., Chen, W., Hu, B., Jagoe, C. T., Kim, H.-Y., Kinder, F. R., Jr., Liu, Y., Lu, Y., McKenna, J., Prashad, M., Ramsey, T. M., Repic, O., Rogers, L., Shieh, W.-C., Wang, R.-M., Waykole, L. |
| Zdroj: |
Organic Process Research & Development; January 2004, Vol. 8 Issue: 1 p101-106, 6p |
| Abstrakt: |
Kilogram-scale syntheses of fragments C1-6 (6) and C9-14 (4) of (+)-discodermolide from common precursor 3 are described. Improved procedures for each step of both fragments were developed by minimizing or eliminating the formation of byproducts that were isolated and characterized in Smith's synthesis. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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