| Autor: |
Kamimoto, Y, Gatmaitan, Z, Hsu, J, Arias, I M |
| Zdroj: |
Journal of Biological Chemistry; July 1989, Vol. 264 Issue: 20 p11693-11698, 6p |
| Abstrakt: |
Gp170 (also known as P-glycoprotein) is a transmembrane glycoprotein which is overexpressed in multidrug-resistant tumor cells and is also found in the apical plasma membrane domain of several normal human and animal tissues. Gp170 has been postulated to function as an energy-dependent efflux pump for cytotoxic drugs. In rat liver, Gp170 is restricted to the bile canalicular domain of the plasma membrane. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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