| Autor: |
Hitchcock-DeGregori, S E, Gerhard, M D, Brown, W E |
| Zdroj: |
Journal of Biological Chemistry; March 1985, Vol. 260 Issue: 5 p3228-3231, 4p |
| Abstrakt: |
We have shown that the platelet tropomyosin binding protein described in the accompanying paper (Gerhard, M. D., DiGirolamo, P. M., and Hitchcock-DeGregori, S. E. (1985) J. Biol. Chem. 260, 3221-3227) is identical with human serum albumin. The immunological determinants are completely shared; the tryptic peptide maps are the same; the proteins comigrate on two-dimensional gels; and the amino acid sequences of the first 33 amino acids are the same. Although human serum albumin in plasma or commercially prepared protein will not bind tropomyosin-Affi-Gel 15, it will bind following purification from plasma by chromatography on hydroxylapatite. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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