Analysis workflow of publicly available RNA-sequencing datasets

Autor: Sanchis, Pablo, Lavignolle, Rosario, Abbate, Mercedes, Lage-Vickers, Sofía, Vazquez, Elba, Cotignola, Javier, Bizzotto, Juan, Gueron, Geraldine
Zdroj: STAR Protocols; 20210101, Issue: Preprints
Abstrakt: Differential gene expression analysis is widely used to study changes in gene expression profiles between two or more groups of samples (e.g., physiological vs. pathological conditions; pre- vs. post-treatment, infected vs. non-infected tissues). This protocol aims to identify gene expression changes in a pre-selected set of genes associated with SARS-CoV-2 viral infection and host cell antiviral response, as well as subsequent gene expression association with phenotypic features using samples deposited in public repositories.
Databáze: Supplemental Index