A Systemic Protein Deviation Score Linked to PD-1+CD8+T Cell Expansion That Predicts Overall Survival in Diffuse Large B Cell Lymphoma

Autor: Ask, Eivind Heggernes, Tschan-Plessl, Astrid, Gjerdingen, Thea Johanne, Sætersmoen, Michelle Lu, Hoel, Hanna Julie, Wiiger, Merete Thune, Olweus, Johanna, Wahlin, Björn E., Lingjærde, Ole Christian, Horowitz, Amir, Cashen, Amanda F., Watkins, Marcus, Fehniger, Todd A., Holte, Harald, Kolstad, Arne, Malmberg, Karl-Johan
Zdroj: Med; February 2021, Vol. 2 Issue: 2 p180-195.e5
Abstrakt: Current prognostic variables can only partly explain the large outcome heterogeneity in diffuse large B cell lymphoma (DLBCL). We aimed to investigate the utility of systems-level protein and immune repertoire profiling for outcome prognostication in DLBCL.
Databáze: Supplemental Index