| Autor: |
Desai, P., Pfeiffer, S. S., Boger, D. L. |
| Zdroj: |
Organic Letters; December 2003, Vol. 5 Issue: 26 p5047-5050, 4p |
| Abstrakt: |
An efficient synthesis of two diastereomers of the chlorofusin cyclic peptide bearing either the l-Asn3/d-Asn-4 or d-Asn3/l-Asn4 stereochemistry is detailed. Four key subunits were prepared, sequentially coupled, and cyclized to provide the two diastereomeric macrocycles. The absolute stereochemistry at the asparagine residues 3 and 4 was assigned as l and d, respectively, by correlating the NMR data of the two diastereomers with that reported for the natural product. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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