| Autor: |
Nazar, Ross N., Tyfield, Linda A., Wong, J. Tze-Fei |
| Zdroj: |
Journal of Biological Chemistry; February 1972, Vol. 247 Issue: 3 p798-804, 7p |
| Abstrakt: |
A continuous and unique variation of stable RNA accumulation with pool levels of nucleoside triphosphates was observed when Escherichia coli(K12 Leu-, rel+) cells were entering into phosphate starvation or recovering spontaneously from inhibition by dinitrophenol. Since the rate of RNA accumulation in these experimental systems surpassed all other known systems exhibiting the same pool levels of nucleoside triphosphates, it is suggested that stable RNA synthesis in these systems was subjected to kinetic regulation by substrate concentrations. This kinetic relationship in vivobetween RNA synthesis and nucleoside triphosphate substrates was sigmoidal in character and exhibited a higher half-saturation constant than the similar relationship obtained with RNA polymerase in vitro. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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