Laparoscopic Sleeve Gastrectomy: Do Lipid Profile and Cardiovascular Risk Predictor Improve in Moderately, Morbidly, and Super Obese Patients?

Autor: Gülşen Atalay, Betül, Parlak, Eda
Zdroj: Bariatric Surgical Practice and Patient Care; 20240101, Issue: Preprints
Abstrakt: Aim:To determine the change in weight loss, lipid profile, and cardiovascular risk predictor (CVRP) in moderately, morbidly, and super obese patients who underwent laparoscopic sleeve gastrectomy (LSG).Subjects and Method:A total of 115 patients who diagnosed as moderately (n= 35), morbidly (n= 60), and super obese (n= 20) underwent LSG, and followed up were evaluated retrospectively. The anthropometric measurements of the patients were evaluated four times: Preoperative, 0–4 months, 5–12 months, and after 1 year. Biochemical findings were evaluated twice as the first and last evaluation.Results:In this study the median percentage of excess weight loss (%EWL) was 77.9% (12.4–214.7), and median percentage of excess BMI loss (%EBL) was 83.3% (34.9–130.9) after 1 year. Total cholesterol and triglyceride levels decreased significantly in morbidly obese patients (p= 0.01, p= 0.02, respectively). C-reactive protein was greatly reduced in moderately obese patients (p= 0.01). Alanine aminotransferase levels improved in moderately and morbidly obese patients after 1 year (p= 0.01, p= 0.002). CVRP decreased significantly from 3.2 to 2.4 after 1 year in all patients (p= 0.04). There was a negative correlation between %EBL (r= −0,857, p= 0.01), percentage of total body weight loss (r= −0.786, p= 0.03), and CVRP in moderately obese patients.Conclusion:In conclusion, we observed that LSG appears to reduce lipid profile and CVRP in moderately and morbidly obese patients in our study.
Databáze: Supplemental Index