Autor: |
Appukkuttan, Prasad, Dehaen, Wim, Eycken, Erik Van der |
Zdroj: |
European Journal of Organic Chemistry; December 2003, Vol. 2003 Issue: 24 p4713-4716, 4p |
Abstrakt: |
Microwave-assisted transition-metal-free Sonogashira-type coupling reactions are described. The reactions are run in water as the sole solvent, without the need for copper(I) or any transition-metal−phosphane complex. The scope of the methodology was tested by reaction of a wide variety of aryl halides and heteroaryl halides. The reaction was also investigated under conventional heating conditions. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003) |
Databáze: |
Supplemental Index |
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