Echtyma gangrenosum caused by coinfection with group A Streptococcusand Staphylococcus aureus: an emerging etiology? Case reports and literature review

Autor: Ulpiano Trillig, Antonio, Miendje Deyi, Véronique Y., Youatou, Pierre, Konopnicki, Deborah
Zdroj: Acta Clinica Belgica: International Journal of Clinical and Laboratory Medicine; January 2021, Vol. 76 Issue: 1 p53-57, 5p
Abstrakt: ABSTRACTEcthyma gangrenosum (EG) is a potentially lethal skin infection, most commonly due to Pseudomonas aeruginosawith bacteremic dissemination and affecting mostly immunocompromised patients. We present two cases of EG in two men in Belgium recently admitted to our hospital, caused by a suspected coinfection by group A Streptococcusand Staphylococcus aureus, with a cutaneous dissemination, in which multiple impetigo lesions were the portal of entry. The first patient had no risk factors nor immunodeficiency, but the second was a homeless man with drug and alcohol abuse and advanced HIV infection. Early management of the condition is crucial, with initial broad spectrum antibiotherapy, rapidly narrowed down to the germs identified and skin lesion debridement if necessary. Any immunocompromising condition must be ruled out in any patient suffering from EG.
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