| Autor: |
Tenforde, Mark W., Boyer-Chammard, Timothée, Muthoga, Charles, Tawe, Leabaneng, Milton, Thandi, Rulaganyang, Ikanyeng, Lechiile, Kwana, Rukasha, Ivy, Leeme, Tshepo B., Govender, Nelesh P., Ngidi, Julia, Mine, Madisa, Molloy, Síle F., Harrison, Thomas S., Lortholary, Olivier, Jarvis, Joseph N. |
| Zdroj: |
Journal of Clinical Microbiology; October 2020, Vol. 59 Issue: 1 |
| Abstrakt: |
High cryptococcal antigen (CrAg) titers in blood are associated with subclinical meningitis and mortality in CrAg-positive individuals with advanced HIV disease (AHD). We evaluated a novel semiquantitative lateral flow assay (LFA), CryptoPS, that may be able to identify individuals with high CrAg titers in a cohort of AHD patients undergoing CrAg screening. In a prospective cohort of patients with AHD (CD4 cell count, =200/µl) receiving CD4 count testing, whole blood was tested for CrAg by CryptoPS and the IMMY LFA; the two assays were conducted by two different operators, each blind to the results of the other assay. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
