Natural killers of cognition

Autor: Papismadov, Nurit, Krizhanovsky, Valery
Zdroj: Nature Neuroscience; January 2021, Vol. 24 Issue: 1 p2-4, 3p
Abstrakt: One of the mechanisms driving aging and neurodegenerative diseases is the accumulation of senescent cells, while their elimination mitigates age-related decline. A new report details how, with aging, changes in the dentate gyrus microenvironment lead to natural-killer-cell-mediated clearance of neurogenic senescent cells, resulting in cognitive decline.
Databáze: Supplemental Index