| Autor: |
Courjon, Johan, Garzaro, Margaux, Roger, Pierre-Marie, Ruimy, Raymond, Lavrut, Thibaud, Chelli, Mikaël, Raynier, Jean-Luc, Chirio, David, Demonchy, Elisa, Cabane, Laura, Jehl, François, Trojani, Christophe, Grillon, Antoine, Goutelle, Sylvain |
| Zdroj: |
Antimicrobial Agents and Chemotherapy; September 2020, Vol. 64 Issue: 12 |
| Abstrakt: |
Intravenous administration of antibiotics is recommended during the early phase of methicillin-susceptible S. aureus(MSSA) bone and joint infection (BJI). We sought to compare the plasma concentrations of cloxacillin administered alternately by continuous and intermittent infusion (CI and ItI) in patients with MSSA BJI. In this prospective crossover trial, patients were randomly assigned to receive either 3 days of CI (two 75-mg/kg 12-h cloxacillin infusions per day) and then 3 days of ItI (four 37. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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