Living-Related Liver Transplantation in Children at Saint-Luc University Clinics : A Seven Year Experience in 77 Recipients

Autor: Reding, R., Chardot, Chr., Paul, K., Veyckemans, F., Obbergh, L. Van, Clety, S. Clement De, Detaille, Th., Clapuyt, Ph., Saint-Martin, Chr., Janssen, M., Lerut, J., Sokal, E., Otte, J.-B.
Zdroj: Acta Chirurgica Belgica; February 2001, Vol. 101 Issue: 1 p17-19, 3p
Abstrakt: AbstractThe Brussels series ol living related liver transplantation (LRLT) in 77 children (<15 years) is reviewed. Median (range) recipient age at liver transplantation was 1.1 year (0.4-13.1). The main indication for LT was biliary atresia in 55/77 cases (71%). The living-related donor was one of the parents in 74 instances. Hepatic segments 2-3 (n = 67) or 2-3-4 (n = 10) were implanted orthotopically, with a median (range) graft weight to recipient body weight ratio of 3.17% (0.91-8.08). No severe complications or significant long-term sequelae were encountered in the living donors. One and five year survival rates were 92% and 89% for the patients, and 90% and 86% for the grafts, respectively. The retransplantation rate was 2/77 (2.6%), the indication being chronic rejection in both instances. In conclusion, LRLT is now a validated procedure in the living donors as well as in pediatric recipients with chronic or acute liver diseases. In the current context of organ shortage, it provides a valuable alternative to cadaveric LT.
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