| Autor: |
Chhabria, Rahul, Mehta, Nihar P., Jain, Nikesh, Handa, Sham R., Mehta, Ashwin B. |
| Zdroj: |
Indian Heart Journal; November-December 2020, Vol. 72 Issue: 6 p603-605, 3p |
| Abstrakt: |
We investigated the diagnostic utility and safety of intracoronary bolus administration of nicorandil compared with intravenous administration of adenosine for evaluating FFR in patients with intermediate (40–70%) coronary stenosis. The FFR values obtained with nicorandil and adenosine showed linear relationship. This correlation is statistically significant with regression coefficient of 0.932 (R2 = 0.834, p < 0.001). The side effects such as bronchospasm, hypotension, and bradycardia were significantly higher after administration of adenosine compared to nicorandil (20% vs. 1.66%, p = 0.001). Intracoronary use of nicorandil seems to be promising in offering the advantages of lesser side effects, similar efficacy, and lesser cost as compared to adenosine. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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