| Autor: |
Xu, Y., Mayhugh, D., Saeed, A., Wang, X., Thompson, R. C., Dominianni, S. J., Kauffman, R. F., Singh, J., Bean, J. S., Bensch, W. R., Barr, R. J., Osborne, J., Montrose-Rafizadeh, C., Zink, R. W., Yumibe, N. P., Huang, N., Luffer-Atlas, D., Rungta, D., Maise, D. E., Mantlo, N. B. |
| Zdroj: |
Journal of Medicinal Chemistry; November 2003, Vol. 46 Issue: 24 p5121-5124, 4p |
| Abstrakt: |
A new series of hPPARα agonists containing a 2,4-dihydro-3H-1,2,4-triazol-3-one (triazolone) core is described leading to the discovery of 5 (LY518674), a highly potent and selective PPARα agonist. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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