| Autor: |
Qayyum, N., Alcocer, L., Maxwell, H., Beattie, T.J., Murphy, A.V., Ramage, I.J., Ahmed, S.F. |
| Zdroj: |
Hormone Research in Paediatrics; May 2003, Vol. 60 Issue: 5 p221-226, 6p |
| Abstrakt: |
AbstractObjectives: To assess stature and skeletal disproportion in children with chronic renal disease. Methods: Cross-sectional study of height (HT), sitting height (SH), subischial leg length (SILL), sitting height/height ratio (SH:HT) and disproportion score (SH SDS minus SILL SDS) in 56 children (M:35) with median age 11.4 years (range 4.5,18.7) with chronic renal disease. Results: There were 19 children with chronic renal insufficiency, 6 receiving peritoneal dialysis and 31 after renal transplant. The median HTSDS for the whole group was 1.21 (2.8, 0.35). The median SH:HT ratio in non-transplanted children and renal transplant were 0.51 (0.49, 0.53) and 0.50 (0.48, 0.53), respectively (p = 0.02). The median disproportion score of the whole group was 3.2 (4.8, 1.8). There was a significant correlation between disproportion score and SH:HT (r = 0.5, p = 0.005). SH:HT ratio was negatively related to duration of illness (r = 0.4, p = 0.005). Conclusion: Children with chronic renal disease have significant body disproportion and this may be due to a disproportionately greater effect of disease and treatment on spinal growth.Copyright © 2003 S. Karger AG, Basel |
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