| Autor: |
Peregud, Danil I., Baronets, Valeria Yu., Lobacheva, Anna S., Ivanov, Alexandr S., Arisheva, Olga S., Garmash, Irina V., Kobalava, Zhanna D., Pirozhkov, Sergey V., Terebilina, Natalia N. |
| Zdroj: |
Annals of Hepatology; January-February 2021, Vol. 20 Issue: 1 |
| Abstrakt: |
Polymorphic variant rs738409 within the PNPLA3gene associates with alcoholic liver cirrhosis (ALC) in heavy drinkers of various ancestry but has not yet been established in the Russian population characterized by high incidence of ALC. PNPLA3rs738409 involvement in the inflammatory process has been proposed as one of the mechanisms of liver dysfunction. Relationship between the PNPLA3polymorphism and the biochemical markers of inflammation in patients with ALC remains unclear. The current study revealed the association between the rs738409 polymorphism, liver cirrhosis and serum cytokines in heavy drinkers in the Russian population. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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