SIV of stump‐tailed macaque (SIVstm) is a divergent Asian isolate

Autor: Khan, Arifa S., Galvin, Teresa A., Jennings, Myra B., Gardner, Murray B., Lowenstine, Linda J.
Zdroj: Journal of Medical Primatology; June 1991, Vol. 20 Issue: 4 p167-171, 5p
Abstrakt: Analysis of molecularly cloned DNAs of SIVs isolated from Asian rhesus macaque (Macaca mulatta; SIVmac) and pig‐tailed macaque (Macaca nemestrina; SIVmne) has indicated a high degree of sequence homology between these viruses. Thus SIVmacand SIVmnemight have originated from the same or very closely related viruses. We have cloned and sequenced a PCR‐amplified segment containing the LTR sequences of SIV originating from a stump‐tailed macaque (Macaca arctoides; SIVstm). Comparative sequence analysis indicates that SIVstmbelongs to the SIV/HIV‐2 group; however, it is genetically distinct from the other members.
Databáze: Supplemental Index