| Autor: |
Balla, Tamas, Gulyas, Gergo, Kim, Yeun Ju, Pemberton, Joshua |
| Zdroj: |
Current Opinion in Physiology; October 2020, Vol. 17 Issue: 1 p149-157, 9p |
| Abstrakt: |
Calcium (Ca2+) ions are critically important in orchestrating countless regulatory processes in eukaryotic cells. Consequently, cells tightly control cytoplasmic Ca2+concentrations using a complex array of Ca2+-selective ion channels, transporters, and signaling effectors. Ca2+transport across various cellular membranes is highly dependent on the intrinsic properties of specific membrane compartments and conversely, local Ca2+changes have profound effects on the membrane lipid composition of such membrane sub-domains. In particular, inositol phospholipids are a minor class of phospholipids that play pivotal roles in the control of Ca2+-dependent signaling pathways. In this review, we will highlight some of the recent advances in this field as well as their impact in defining future research directions. |
| Databáze: |
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