Burden of prematurity-associated recurrent wheezing: caregiver missed work in the D-Wheeze trial

Autor: Ledingham, Lauren, Tatsuoka, Curtis, Minich, Nori, Ross, Kristie R., Kerns, Leigh Ann, Wagner, Carol L., Fuloria, Mamta, Groh-Wargo, Sharon, Zimmerman, Teresa, Hibbs, Anna Maria
Zdroj: Journal of Perinatology; January 2021, Vol. 41 Issue: 1 p69-76, 8p
Abstrakt: Objective: This study describes the burden of prematurity-associated wheezing in black infants with respect to caregiver missed work. Study design: We analyzed data from the D-Wheeze trial (ClinicalTrials.gov identifier NCT01601847). Black infants between 28–0/7 to 36–6/7 weeks’ gestational age at birth receiving <28 days of supplemental oxygen were enrolled. The primary outcome was missed work to care for the infant in the first year. Results: 147/277 (53.1%) infants had caregivers who reported time off. In an adjusted model, vitamin D supplementation (OR 0.52 [95% CI 0.30–0.89]; P?=?0.018), recurrent wheeze (OR 2.26 [95% CI, 1.15–4.44]; P?=?0.018), and other children in the household <5 years old (OR 0.45 [95% CI 0.26–0.78]; P?=?0.004) were significantly associated with caregiver missed work. Conclusions: Black premature infants had a significant burden of caregiver missed work, emphasizing the impact of prematurity-associated wheezing.
Databáze: Supplemental Index
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