The RESOLUTE consortium: unlocking SLC transporters for drug discovery

Autor: Superti-Furga, Giulio, Lackner, Daniel, Wiedmer, Tabea, Ingles-Prieto, Alvaro, Barbosa, Barbara, Girardi, Enrico, Goldmann, Ulrich, Gürtl, Bettina, Klavins, Kristaps, Klimek, Christoph, Lindinger, Sabrina, Liñeiro-Retes, Eva, Müller, André C., Onstein, Svenja, Redinger, Gregor, Reil, Daniela, Sedlyarov, Vitaly, Wolf, Gernot, Crawford, Matthew, Everley, Robert, Hepworth, David, Liu, Shenping, Noell, Stephen, Piotrowski, Mary, Stanton, Robert, Zhang, Hui, Corallino, Salvatore, Faedo, Andrea, Insidioso, Maria, Maresca, Giovanna, Redaelli, Loredana, Sassone, Francesca, Scarabottolo, Lia, Stucchi, Michela, Tarroni, Paola, Tremolada, Sara, Batoulis, Helena, Becker, Andreas, Bender, Eckhard, Chang, Yung-Ning, Ehrmann, Alexander, Müller-Fahrnow, Anke, Pütter, Vera, Zindel, Diana, Hamilton, Bradford, Lenter, Martin, Santacruz, Diana, Viollet, Coralie, Whitehurst, Charles, Johnsson, Kai, Leippe, Philipp, Baumgarten, Birgit, Chang, Lena, Ibig, Yvonne, Pfeifer, Martin, Reinhardt, Jürgen, Schönbett, Julian, Selzer, Paul, Seuwen, Klaus, Bettembourg, Charles, Biton, Bruno, Czech, Jörg, de Foucauld, Hélène, Didier, Michel, Licher, Thomas, Mikol, Vincent, Pommereau, Antje, Puech, Frédéric, Yaligara, Veeranagouda, Edwards, Aled, Bongers, Brandon J., Heitman, Laura H., IJzerman, Ad P., Sijben, Huub J., van Westen, Gerard J.P., Grixti, Justine, Kell, Douglas B., Mughal, Farah, Swainston, Neil, Wright-Muelas, Marina, Bohstedt, Tina, Burgess-Brown, Nicola, Carpenter, Liz, Dürr, Katharina, Hansen, Jesper, Scacioc, Andreea, Banci, Giulia, Colas, Claire, Digles, Daniela, Ecker, Gerhard, Füzi, Barbara, Gamsjäger, Viktoria, Grandits, Melanie, Martini, Riccardo, Troger, Florentina, Altermatt, Patrick, Doucerain, Cédric, Dürrenberger, Franz, Manolova, Vania, Steck, Anna-Lena, Sundström, Hanna, Wilhelm, Maria, Steppan, Claire M.
Zdroj: Nature Reviews Drug Discovery; July 2020, Vol. 19 Issue: 7 p429-430, 2p
Abstrakt: The Innovative Medicines Initiative Consortium RESOLUTE has started to develop tools and produce data sets to de-orphanize transporters in the solute carrier protein (SLC) superfamily, thereby lowering the barrier for the scientific community to explore SLCs as an attractive drug target class.
Databáze: Supplemental Index
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