cGAS-STING–mediated DNA sensing maintains CD8+T cell stemness and promotes antitumor T cell therapy
| Autor: | Li, Wenwen, Lu, Lu, Lu, Juanjuan, Wang, Xinran, Yang, Chao, Jin, Jingsi, Wu, Lingling, Hong, Xiaochuan, Li, Fanlin, Cao, Dongqing, Yang, Yuanqin, Wu, Meng, Su, Bing, Cheng, Jinke, Yang, Xuanming, Di, Wen, Deng, Liufu |
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| Zdroj: | Science Translational Medicine; June 2020, Vol. 12 Issue: 549 |
| Abstrakt: | Cell-intrinsic cGAS-STING–mediated DNA sensing promotes the formation of stem cell–like CD8+T cells for effective cancer T cell therapy. |
| Databáze: | Supplemental Index |
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