Treatment of Group A Streptococcal Pharyngitis in Children: Comparison of Lincomycin and Penicillin G Given Orally and Benzathine Penicillin G Given Intramuscularly
Autor: | Howie, Virgil M., Ploussard, John H. |
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Zdroj: | American Journal of Diseases of Children; June 1971, Vol. 121 Issue: 6 p477-480, 4p |
Abstrakt: | Two hundred twenty-eight children with group A β-streptococcal pharyngitis, or carrier state, were treated with one of three treatment regimes from September 1969 to March 1970 and followed-up with throat cultures at 5, 14, 31, and 60 days. Treatment groups were benzathine penicillin G given intramuscularly, and penicillin G potassium and lincomycin hydrochloride monohydrate, administered orally. Lincomycin hydrochloride monohydrate given orally in recommended dosages for ten days was found to be as effective as benzathine penicillin G given intramuscularly (cure rates at 31 days, 86.8% and 88.9%, respectively). Both drugs were more effective than penicillin G given orally for ten days (31-day cure rate, 70%). The 60-day cure rates were 84% for lincomycin given orally, 72% for benzathine penicillin G given intramuscularly, and 60% for penicillin G given orally. |
Databáze: | Supplemental Index |
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