Thiabendazole in Visceral Larva Migrans

Autor: Aur, Rhomes J.A., Pratt, Charles B., Johnson, Warren W.
Zdroj: American Journal of Diseases of Children; March 1971, Vol. 121 Issue: 3 p226-229, 4p
Abstrakt: Thiabendazole, a broad spectrum anti-helminthic agent, was administered to three children with visceral larva migrans in a dosage of 20 to 50 mg/kg daily for seven to ten days. The children had presented with fever, weight loss, anemia, lymphoadenopathy, hepatosplenomegaly, perihilar infiltrates, leukocytosis, and eosinophilia. This course was repeated after a four-week interval. After thiabendazole therapy, they demonstrated rapid clinical and laboratory improvement, contrasting with the prolonged duration of disease when no therapy is given. There was no evidence of drug-associated toxicity.
Databáze: Supplemental Index