Radiation Reaction in Ataxia Telangiectasia

Autor: Morgan, John L., Holcomb, Thomas M., Morrissey, Robert W.
Zdroj: American Journal of Diseases of Children; November 1968, Vol. 116 Issue: 5 p557-558, 2p
Abstrakt: AN UNTOWARD response to radiotherapy in a patient with ataxia telangiectasia and malignancy was reported recently.1 The present case is reported to provide evidence of a similar experience with a patient who also had this rare disease complex. REPORT OF A CASE The patient was a 9-year-old white boy who was followed at Wilford Hall USAF Hospital from Oct 5, 1964, until his death on May 1, 1967. He was the product of a full-term gestation and appeared normal during the first year of life. When he started to walk at 15 months of age, ataxia was noted. The child had frequent episodes of bronchitis and ear infections during the first four years of life, and when he was 6 years old, he began having repeated bouts of pneumonia. At age 7, telangiectasia of the auricles and of the palpebral and bulbar conjunctiva became evident, and the diagnosis of
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