Transient Edema And Hypoproteinemia: Possible Menetrier's Disease

Autor: PITTMAN, FRED E., HARRIS, RUTH C., BARKER, HAROLD G.
Zdroj: American Journal of Diseases of Children; August 1964, Vol. 108 Issue: 2 p189-197, 9p
Abstrakt: Idiopathic transient edema and hypoproteinemia of childhood has been a recognized clinical entity for several years.1-5 Recently studies have indicated that in the absence of proteinuria, increased intestinal degradation of protein (exudative enteropathy, protein-losing gastroenteropathy) plays an important role in the genesis of the edema and hypoproteinemia.6,7 Unlike children who have had persistent edema and hypoproteinemia with increased gastrointestinal protein degradation,8-11 only one of the patients with transient idiopathic edema and hypoproteinemia has had evidence of gastrointestinal pathology. This patient, a 3-year-old child reported by Degnan,5 had "the presence and persistence of large gastric folds on gastrointestinal series, suggesting hypertrophic gastritis."The purpose of this paper is to report a case of transient severe edema and hypoproteinemia in a 5-year-old child who was shown to have increased intestinal degradation and decreased synthetic activity of albumin associated with transient giant hypertrophy of the gastric mucosa. REPORT OF
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