Third-Generation Sequencing in the Clinical Laboratory: Exploring the Advantages and Challenges of Nanopore Sequencing

Autor: Petersen, Lauren M., Martin, Isabella W., Moschetti, Wayne E., Kershaw, Colleen M., Tsongalis, Gregory J.
Zdroj: Journal of Clinical Microbiology; December 2019, Vol. 58 Issue: 1
Abstrakt: Metagenomic sequencing for infectious disease diagnostics is an important tool that holds promise for use in the clinical laboratory. Challenges for implementation so far include high cost, the length of time to results, and the need for technical and bioinformatics expertise. However, the recent technological innovation of nanopore sequencing from Oxford Nanopore Technologies (ONT) has the potential to address these challenges.
Databáze: Supplemental Index