The impact of micelle size and increased absorption of ubiquinone using a novel delivery system (AquaCelle®)

Autor: Briskey, David, Sax, Andrew T, Mallard, Alistair R, Ng, Charlie, Rao, Amanda
Zdroj: International Journal of Pharmacokinetics; March 2020, Vol. 4 Issue: 2
Abstrakt: Aim:The objective of this study was to determine whether the use of a self-emulsifying drug delivery system AquaCelle®, could improve the absorption of CoQ10. Materials & methods:Fifty-seven healthy males and females completed this study with the primary outcome as change in plasma absorption of CoQ10over a 10-h period. Results:All AquaCelle groups significantly increased CoQ10concentrations up to three-times that of the standard CoQ10supplement. Ubiquinone with AquaCelle achieved an equivalent absorption to ubiquinol. Conclusion:The novel delivery system AquaCelle demonstrates superior absorption for the supply of ubiquinone when compared with a standard ubiquinone extract. These results further indicate that ubiquinone with AquaCelle absorbs as effectively as the typically superior absorbing ubiquinol at the same 100 mg dose.
Databáze: Supplemental Index