| Autor: |
Menakh, Mouna, Mahdi, Djahida, Boutellaa, Saber, Zellagui, Amar, Lahouel, Mesbah, Bensouici, Chawki |
| Zdroj: |
Acta Scientifica Naturalis; March 2020, Vol. 7 Issue: 1 p33-45, 13p |
| Abstrakt: |
The current study investigated the protective effect of Hertia cheirifolia L. n-butanol extract on oxidative stress in vitro by measuring lipid peroxidation (MDA) level and superoxide anion (O2•-) production in liver and heart mitochondria of rat. In addition, the antioxidant potential of H. cheirifolia n-butanol extract was evaluated by using five methods: ABTS•+, O2•-, Bleaching of β-carotene in linoleic acid, CUPRAC and Ferric reducing power. The results indicated that n-butanol extract contained large amounts of total phenolics (203.52±1.81 mg GAE/g) and flavonoids (104.86±0.57 mg QE/g), and had an interesting antioxidant activity and protective effect on mitochondrial oxidative stress. Therefore, H. cheirifolia n-butanol extract may serve as potential source of natural antioxidant for pharmaceutical applications. |
| Databáze: |
Supplemental Index |
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