| Autor: |
ZUCKER-FRANKLIN, DOROTHEA, FRANKLIN, EDWARD C., COOPER, NORMAN S. |
| Zdroj: |
Blood; July 1962, Vol. 20 Issue: 1 p56-64, 9p |
| Abstrakt: |
Lymph nodes of three patients with macroglobulinemia of Waldenström were studied in tissue culture and shown to synthesize 19S γ-globulin in vitro. Lymph node imprints, bone marrow, and buffy coat smears of the same patients consisted almost entirely of lymphocytes. When these were stained with fluorescein-conjugated antiserum to macroglobulin, large and medium-sized lymphocytes and lymphoblasts rather than mature lymphocytes or plasma cells were shown to contain the protein. It is suggested that 19S γ-globulin may also be synthesized by cells belonging to the lymphoid series under normal circumstances. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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