Autor: |
BETHARD, W. F., WISSLER, R. W., THOMPSON, J. S., SCHROEDER, M. A., ROBSON, M. J. |
Zdroj: |
Blood; February 1958, Vol. 13 Issue: 2 p146-155, 10p |
Abstrakt: |
1. The distribution of Fe59 in plasma, bone marrow, erythrocytes, liver, and spleen was determined at specified intervals after single intravenous injections of the radioisotope into normal and protein-deficient rats. 2. In normal rats, injected radioiron followed the usual metabolic pathways; i.e., through bone marrow to erythrocytes, with small, consistent amounts to liver and spleen. 3. In protein-deficient animals normal Fe59 time-concentration relationships were disrupted completely. 4. Less iron was recovered from the tissues of protein-deficient rats than from normal animals. 5. Storage iron in liver and spleen was not conjugated with polysaccharide, even though tissue protein was seriously depleted. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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