Isolation and Structure Determination of an Antimicrobial Ester from a Marine Sediment-Derived Bacterium

Autor: Schumacher, R. W., Talmage, S. C., Miller, S. A., Sarris, K. E., Davidson, B. S., Goldberg, A.
Zdroj: Journal of Natural Products; September 2003, Vol. 66 Issue: 9 p1291-1293, 3p
Abstrakt: A new compound, assigned the trivial name bonactin (1), has been isolated from the liquid culture of a Streptomyces sp. BD21-2 obtained from a shallow-water sediment sample collected at Kailua Beach, Oahu, Hawaii. Structure elucidation employed one- and two-dimensional NMR, HRFABMS, IR, and chemical analysis. Bonactin displayed antimicrobial activity against both Gram-positive and Gram-negative bacteria as well as antifungal activity.
Databáze: Supplemental Index