| Autor: |
Winkelmann, JC, Leto, TL, Watkins, PC, Eddy, R, Shows, TB, Linnenbach, AJ, Sahr, KE, Kathuria, N, Marchesi, VT, Forget, BG |
| Zdroj: |
Blood; July 1988, Vol. 72 Issue: 1 p328-334, 7p |
| Abstrakt: |
Overlapping cDNA clones, totaling 3.3 kilobases (kb) in length, which encode over 50% of the human erythrocyte beta-spectrin subunit, were isolated by antibody screening of a lambda gt11 expression library constructed from human fetal liver mRNA. The amino acid sequence of the C-terminus of beta-spectrin was derived. The size of beta-spectrin mRNA in human erythroleukemia cells was found to be 7.5 kb. Erythrocyte beta- spectrin is encoded by a gene located on human chromosome 14, as determined by cDNA hybridization to human X mouse somatic cell hybrids. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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