Acute lymphoblastic leukemia followed by chronic myelocytic leukemia

Autor: Tosato, G, Whang-Peng, J, Levine, AS, Poplack, DG
Zdroj: Blood; November 1978, Vol. 52 Issue: 5 p1033-1036, 4p
Abstrakt: Second hematologic malignancies occur rarely in patients previously treated for leukemia. This report describes a patient with acute lymphoblastic leukemia who remained in complete remission for 5 yr and then developed chronic myelocytic leukemia (CML). The original lymphoblasts were associated with a partial deletion of chromosome 21, while CML was associated with a classic Philadelphia marker, indicating the independent origin of the two leukemias.
Databáze: Supplemental Index