Biostatic Behavior of Side Chain Charged Polycations and Polymer-Ag Complexes

Autor: Rivas, BernabéL., Pereira, EduardoD., Mondaca, MariaA.
Zdroj: Polymer Bulletin; 20030701, Vol. 50 Issue: 5-6 p327-333, 7p
Abstrakt: Summary Poly[(3-methacryloylamino)propyl]trimethylammonium)chloride (PMF'TA), and poly (2-acrylamido-2-methyl-1-propane sulfonic acid) (PAPSA) were synthesized by radical polymerization. Three copolymers of (3-methacryloylamino)propyl] trimethylammonium chloride and 2-acrylamido-2-methyl-1-propane sulfonic acid P(MPTA-co-APSA) with different feed monomer mol ratios were also synthesized by radical polymerization. These polymer materials and the commercial poly(vinylpyrro1idone- co-2-dimethylaminoethyl methacrylate) quaternized P(VP- co- DMAEM) were purified by ultrafiltration membranes and subsequently their complexes with Ag(I) were prepared. Antibacterial activity of all these polymers, was investigated against Escherichia coli (6538P), and Staphylococcus aureus (ATCC 28922), using the National Comittee for Clinical Laboratory Standards method [1]. None of these compounds exhibited biocidal or biostatic action against E. coli, and only PMTA and P(VP- co-DMAEM) exhibited some action against S. aureus.
Databáze: Supplemental Index