| Autor: |
Osband, ME, Cohen, EB, Miller, BR, Shen, YJ, Cohen, L, Flescher, L, Brown, AE, McCaffrey, RP |
| Zdroj: |
Blood; July 1981, Vol. 58 Issue: 1 p87-90, 4p |
| Abstrakt: |
It is increasingly clear that histamine mediates a variety of lymphocyte functions. Further understanding of these mechanisms requires a method for the analysis of histamine membrane receptors on the lymphocyte surface. We report now a biochemical technique for the identification and quantitation of specific histamine H1 and H2 receptors of lymphocytes. The method can be performed on small numbers of formaldehyde-fixed cells. The data this assay yields, together with that resulting from the flow cytometric analysis of histamine receptor distribution (a technique we have previously described), will be a powerful tool in the study of histamine mediation of lymphocyte function. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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