| Autor: |
Zou, Guoyou, Zheng, Minqian, Chen, Wang, He, Xiao, Cang, Dingwei |
| Zdroj: |
Journal of International Medical Research; 20240101, Issue: Preprints |
| Abstrakt: |
Objective This study was performed to explore the effect of intra-articular injection of autologous platelet-rich plasma (PRP) on refractory pain after low-grade medial collateral ligament (MCL) injury.Methods In total, 52 patients with refractory pain after low-grade knee MCL injury were treated by intra-articular injection of autologous PRP. Every patient received a 5-mL intra-articular injection of autologous PRP once weekly for 3 weeks. All patients were evaluated by the International Knee Documentation Committee (IKDC) Subjective Knee Evaluation Form score before treatment and 1, 3, and 6 months after treatment. Magnetic resonance imaging of the knee was performed to observe the healing of the MCL injury 6 months after treatment.Results After one injection, the patients’ pain was greatly decreased and they stopped taking nonsteroidal anti-inflammatory drugs. The IKDC Subjective Knee Evaluation Form scores were significantly better after than before treatment; however, there were no significant differences among the various post-treatment time points. Magnetic resonance imaging showed that the low-grade MCL injury had completely healed, and no edema was present around the MCL.Conclusions Intra-articular injection of autologous PRP is an effective treatment for refractory pain after low-grade MCL injury. |
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