| Autor: |
Solo, Eddie S., Nakajima, Chie, Kaile, Trevor, Bwalya, Precious, Mbulo, Grace, Fukushima, Yukari, Chila, Sylvia, Kapata, Nanthan, Shah, Yogendra, Suzuki, Yasuhiko |
| Zdroj: |
Journal of Global Antimicrobial Resistance; September 2020, Vol. 22 Issue: 1 p302-307, 6p |
| Abstrakt: |
•Genetic mechanism of resistance of Mycobacterium tuberculosisto RIF and INH in Zambia was previously unreported.•96.0% (95/99) of MDR-TB isolates in Zambia carried mutations in both rpoBand katGgenes.•No mutations were detected among pan-susceptible isolates.•Extraordinary high katGmutation rate among M. tuberculosisisolates in Zambia compared with other regional countries.•Difference in katGmutation rate may separate cross-boundary transmission of MDR-TB from other African nations. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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