Selective Monoacylation of Symmetrical Diamines via Prior Complexation with Boron

Autor: Zhang, Z., Yin, Z., Meanwell, N. A., Kadow, J. F., Wang, T.
Zdroj: Organic Letters; September 2003, Vol. 5 Issue: 19 p3399-3402, 4p
Abstrakt: Pretreatment of a symmetrical primary or secondary diamine with 9-BBN prior to the addition of an acyl chloride significantly suppressed undesired diacylation, and the product of monoacylation predominated. The reactive preference is interpreted as the result of a selective deactivation of one nitrogen atom of the diamine by 9-BBN.
Databáze: Supplemental Index