| Autor: |
De Boer, Alberdina W., Van Schaijk, Theodora C.J.G., Willems, Hans L., De Haan, Anton F.J., Monnens, Leo A.H., Schröder, Cornelis H. |
| Zdroj: |
Peritoneal Dialysis International; November 1999, Vol. 19 Issue: 6 p572-577, 6p |
| Abstrakt: |
Objectives To study longitudinal changes in trans-capillary ultrafiltration (TCUF) and marker clearance (MC), as a reflection of lymphatic absorption, in children on peritoneal dialysis (PD). To present data on fluid kinetics in infants younger than 2.5 years, using an intraperitoneal volume of 1200 mL/m2body surface area (BSA).Design The study involved a 4-hour dwell of 1200 mL/m2BSA of dialysis fluid containing 3.86% glucose with Dextran 70 as volume marker. Cumulative TCUF and cumulative MC were measured.Setting A tertiary-care university hospital.Patients A follow-up period of 33 months of serial (1 – 4) peritoneal equilibration tests (PETs) was studied in 20 children with a median age of 6.4 years (range 2.1 – 15.4 years). Fluid kinetics in 5 additional infants with a median age of 1.4 years (range 0.5 – 2.5 years) was measured.Results Cumulative TCUF was 1041 mL/1.73 m2at 1 – 3 months after start of PD, 1026 mL/1.73 m2at 7 – 9 months, 1021 mL/1.73 m2at 11 – 13 months, and 756 mL/ 1.73 m2at 26 – 33 months (NS). Cumulative MC was 235 mL/1.73 m2at 1 – 3 months after start of PD, 311 mL/ 1.73 m2at 7 – 9 months, 395 mL/1.73 m2at 11 – 13 months, and 509 mL/1.73 m2at 26 – 33 months (NS). In infants, cumulative TCUF was 755 ± 237 mL/1.73 m2; cumulative MC was 400 ± 214 mL/1.73 m2.Conclusions Transcapillary ultrafiltration and marker clearance do not change in children > 2.5 years during the period studied. Fluid kinetics does not differ between infants < 2.5 years and older children when intraperitoneal volumes of 1200 mL/m2BSA are used. |
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