| Autor: |
Joshi, Sonal S, Cheong, Han, Meller, Victoria H |
| Zdroj: |
Fly; January 2014, Vol. 8 Issue: 1 p58-62, 5p |
| Abstrakt: |
We describe a method for generation and maintenance of translocations that move large autosomal segments onto the Ychromosome. Using this strategy we produced (2;Y) translocations that relocate between 1.5 and 4.8 Mb of the 2ndchromosome.. All translocations were easily balanced over a male-specific lethal 1(msl-1) mutant chromosome. Both halves of the translocation carry visible markers, as well as P-element ends that enable molecular confirmation. Halves of these translocations can be separated to produce offspring with duplications and with lethal second chromosome deficiencies . Such large deficiencies are otherwise tedious to generate and maintain. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
