Long noncoding RNA SNHG12integrates a DNA-PK–mediated DNA damage response and vascular senescence

Autor: Haemmig, Stefan, Yang, Dafeng, Sun, Xinghui, Das, Debapria, Ghaffari, Siavash, Molinaro, Roberto, Chen, Lei, Deng, Yihuan, Freeman, Dan, Moullan, Norman, Tesmenitsky, Yevgenia, Wara, A.K.M. Khyrul, Simion, Viorel, Shvartz, Eugenia, Lee, James F., Yang, Tianlun, Sukova, Galina, Marto, Jarrod A., Stone, Peter H., Lee, Warren L., Auwerx, Johan, Libby, Peter, Feinberg, Mark W.
Zdroj: Science Translational Medicine; February 2020, Vol. 12 Issue: 531
Abstrakt: Deficiency of lncRNA SNHG12impairs DNA damage repair in the vessel wall and predisposes to vascular senescence and atherosclerosis.
Databáze: Supplemental Index